Editorial: The Ethics for Early Evidence

  Dr. Steven Pearson of the Institute for Clinical and Economic Review at the ITA recently published an editorial with colleagues in the New England Journal of Medicine titled “The Ethics of Early Evidence – Preparing for a Possible Breakthrough in Alzheimer’s Disease.”  Researchers recently demonstrated the drug bexarotene is effective in treating Alzheimer’s disease … Read more

Nearly 800,000 deaths prevented due to declines in smoking

NIH study examines the impact of tobacco control policies and programs, and the potential for further reduction in lung cancer deaths

Twentieth-century tobacco control programs and policies were responsible for preventing more than 795,000 lung cancer deaths in the United States from 1975 through 2000, according to an analysis funded by the National Cancer Institute (NCI), part of the National Institutes of Health.

It Costs More, but Is It Worth More?

By Ezekiel J. Emanuel and Steven D. Pearson   If you want to know what is wrong with American health care today, exhibit A might be the two new proton beam treatment facilities the Mayo Clinic has begun building, one in Minnesota, the other in Arizona, at a cost of more than $180 million dollars … Read more

Early breast cancer screening may help some: study

Oct 6 (Reuters) – Starting breast cancer screening as early as age 25 may help women who carry a genetic mutation linked to a higher risk of cancer live longer, according to a U.S. study.

Researchers, whose findings were reported in the journal Cancer, looked at which breast cancer screenings — mammogram or magnetic resonance imaging (MRI) — were effective in women who carry the gene mutations BRCA1 and BRCA2, known to increase the risk of breast and ovarian cancer. They looked at women aged 25, 30, 35 and 40 years old.

What to know before giving, getting a CT scan

The use of CT scans has grown tremendously in the past three decades. The imaging tests, first widely used in the mid-1970s, have become a valuable tool for pinpointing tumors and blood clots, monitoring heart disease, and reducing the need for exploratory surgery. But there is evidence that their use has outpaced need.

The American Medical Association is taking public comment through the end of this week on a proposal to control use of the tests. There are a couple of good reasons for doing that.

Busting cardiac CTA myths

There are a few fairly long-standing myths about cardiac CT angiography (CTA). The top two emphasize its exploding use and high costs. Yet, several studies published in this month's American Journal of Roentgenology attempted to put those myths to bed. David C. Levin, MD, of the Center for Research on the Utilization of Imaging Services … Read more

Imaging and Comparative-effectiveness Research: A Conversation With William T. Thorwarth Jr, MD

Comparative-effectiveness research has become the platform for several organizations, including the Institute for Clinical and Economic Review (ICER). Based at the Institute for Technology Assessment at Massachusetts General Hospital in Boston, ICER’s mission is to lead comparative-effectiveness–research innovation through methods that the organization says integrate considerations of clinical benefit and economic value through a unique … Read more

Uterine Fibroid Treatment Increases Quality of Life

(Ivanhoe Newswire) — Women who received one of three treatments for uterine fibroids at Brigham and Women's Hospital in Boston said their symptoms diminished and their quality of life significantly increased, according to this study.   Uterine fibroids are benign pelvic tumors that occur in as many as one in five women during their childbearing … Read more