With Testicular Cancer, CT Scan Benefit May Beat Risks

HealthDay reports on research led by Pari Pandharipande, MD concerning the risks of repeat CT scans for Testicular Cancer Patients. News Coverage: RSNA Press Release – http://www2.rsna.org/timssnet/media/pressreleases/pr_target.cfm?ID=659 Healthimaging.com – http://www.healthimaging.com/topics/diagnostic-imaging/lifetime-risk-estimates-may-distort-risk-radiation-induced-cancer AuntMinnie.com – http://www.auntminnie.com/index.aspx?sec=ser&sub=def&pag=dis&ItemID=101972  

Rescreening of Persons with a Negative Colonoscopy Result

A recent study by ITA investigators led by Amy Knudsen, PhD suggests that it may be reasonable to rescreen for colorectal cancer with methods other than colonoscopy following an initial negative exam. Using a microsimulation model of colorectal cancer, researchers found that rescreening at age 60 with colonoscopy every 10 years, CT colonography (aka “virtual … Read more

Research Results: Industry Sponsorship Negatively Influences Physicians’ Perceptions of Findings

Dr. Susannah L. Rose, PCORT alumna, was part of a collaborative team to examine how clinical-trial funding effects the interpretation of trial results by physicians.  Currently, all major clinical trials now include disclosures detailing who funded the study to ensure transparency. However, is it possible that this transparency is actually hurting research? One might assume that the methodological rigor of the study matters to physicians more than the disclosure.  However, in a new study, researchers at have found that pharmaceutical industry sponsorship of a research study negatively influences physicians’ perceptions of the study and their willingness to believe and act on the research findings. This study was published in the September 20, 2012 issue of the New England Journal of Medicine (NEJM).

NCI Monograph: Impact of Reduction in Smoking on Lung Cancer Mortality

  Dr. Pamela McMahon and ITA research staff collaborated with other mathematical modelers as part of the National Cancer Institute’s Cancer Intervention and Surveillance Modeling Network to the special issue of Risk Analysis: The Impact of the Reduction in Tobacco Smoking on  U.S. Lung Cancer Mortality (1975-2000): Collective Results from the Cancer Intervention and Surveillance … Read more

Study Results: Aspirin May Head Off Esophagus Disorder

  The New York Times recently spotlighted a scientific publication by Dr. Chin Hur and other ITA research staff that investigated clinical risk factors to better identify which patients should be screening for Barrett’s Esophagus.  In a case-controlled study of 434 patients with Barrett’s Esophagus, researchers found that current use of aspirin reduced the risk … Read more

Editorial: The Ethics for Early Evidence

  Dr. Steven Pearson of the Institute for Clinical and Economic Review at the ITA recently published an editorial with colleagues in the New England Journal of Medicine titled “The Ethics of Early Evidence – Preparing for a Possible Breakthrough in Alzheimer’s Disease.”  Researchers recently demonstrated the drug bexarotene is effective in treating Alzheimer’s disease … Read more

Nearly 800,000 deaths prevented due to declines in smoking

NIH study examines the impact of tobacco control policies and programs, and the potential for further reduction in lung cancer deaths

Twentieth-century tobacco control programs and policies were responsible for preventing more than 795,000 lung cancer deaths in the United States from 1975 through 2000, according to an analysis funded by the National Cancer Institute (NCI), part of the National Institutes of Health.

It Costs More, but Is It Worth More?

By Ezekiel J. Emanuel and Steven D. Pearson   If you want to know what is wrong with American health care today, exhibit A might be the two new proton beam treatment facilities the Mayo Clinic has begun building, one in Minnesota, the other in Arizona, at a cost of more than $180 million dollars … Read more

Early breast cancer screening may help some: study

Oct 6 (Reuters) – Starting breast cancer screening as early as age 25 may help women who carry a genetic mutation linked to a higher risk of cancer live longer, according to a U.S. study.

Researchers, whose findings were reported in the journal Cancer, looked at which breast cancer screenings — mammogram or magnetic resonance imaging (MRI) — were effective in women who carry the gene mutations BRCA1 and BRCA2, known to increase the risk of breast and ovarian cancer. They looked at women aged 25, 30, 35 and 40 years old.